Spacer engineering in nanoparticle–peptide conjugates boosts targeting specificity for tumor-associated antigens
Résumé
Orientation and steric hindrance decrease the efficiency for an antibody to attach to its specific receptor. Giving flexibility to a dendronized peptide through a small PEG fragment increases the peptides affinity to cellular receptors.
Domaines
ChimieOrigine | Publication financée par une institution |
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licence |