HEK293 Cells Congenital myopathy Amyotrophic Lateral Sclerosis/genetics Deficiency Amyotrophic lateral sclerosis Jonction Neuromusculaire NMJ Actionable genes Aged Rare diseases Actin cytoskeleton HypoPP ¼ hypokalaemic periodic paralysis M3243AG Heart failure Amyloid Nondystrophic myotonias Awareness Acetylcholine receptor clustering Gene Expression Regulation MuSK Chemokines Cell Cycle Proteins/chemistry/genetics/metabolism Neuromuscular junction CMS Cytokines Gating pore current Abbreviations CMAP ¼ compound muscle action potential Paramyotonia congenita Cholinergic Adult SMA Neuromuscular disease Frontotemporal Dementia/genetics Autoimmune Cognitive decline Knockout mouse Congenital myasthenic syndrome Aging Clinical trial Experimental disease models MBNL HSP70 Heat-Shock Proteins/genetics/metabolism IL-22 binding protein isoform Database Clinical trials Frontotemporal lobar degeneration Mexiletine Precision medicine Jonction neuro musculaire Ca V Genetic Association Studies Diseases Lithium chloride ALS HDAC motor neuron neuromuscular junction reinnervation Humans Developmental Jonction neuromusculaire Longitudinal progression Acetylcholinesterase Non-dystrophic myotonia Embryo COVID-19 Dimerization Receptors Wnt NMJ Hypokalaemic periodic paralysis Hereditary/genetics Myotonia congenita IL22RA2 Brain Treatment delay COS Cells Calcium channel Cluster Analysis MRC ¼ Medical Research Council Cercopithecus aethiops Myotonic Dystrophy Body Patterning Biological Markers Congenital myasthenic syndromes Agrin Disability Minigene Epidemiology Expression Synaptotagmin2 Conduction disease Alzheimer's disease CLS Chloride channel GFPT1 Acetyltransferase Mutation 80 and over Drainage Motoneuron Female LRP4 Butyrylcholinesterase Distal myopathy Animals Multiple sclerosis